Inflation Reduction Act Impact on Pharmaceutical Investment: Insights from Investor Interviews

6 months ago


AUTHORS

William J. Canestaro, PhD, MSc, of the University of Washington; Julie A. Patterson, PharmD, PhD, and Jonathan D. Campbell, PhD, MS, of the National Pharmaceutical Council.

PUBLICATION

“Inflation Reduction Act Impact on Pharmaceutical Investment: Insights From Investor Interviews”

Health Affairs Scholar 

 

ABSTRACT

OBJECTIVES

There is limited direct measurement of whether the Inflation Reduction Act is beginning to influence investment strategy and decisions.

METHODS

Using a standardized guide, authors interviewed life science investors from a range of stages, investment sizes, and fund types to explore how incentives under the IRA have impacted investment decisions.

RESULTS

Authors interviewed 31 active investors and found: 

  • Over 90% had discussed the law within their firm. 
     
  • While 71% reported a lack of firm-wide consensus as to the IRA’s precise potential impacts, 87% reported that the IRA was making it more challenging to bring innovative new medicines to market. 
     
  • All but one investor reported they were more likely to consider a larger launch indication for products they invest in, and 77% reported the IRA influenced small molecule investing.

CONCLUSION

Early signals of IRA impact on investor strategy include favoring a larger population launch and reduced small molecule investing. Noting stated preference and other study limitations, investors signaled continued interest in certain high Medicare utilization drugs. Buy-side investment impacts remain understudied.



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